A Pharmacokinetic Study of Vaginally and Intravenously Administered Oxytocin

Inclusion Criteria: * Post-menopausal women with vaginal atrophy as judged by the investigator * Willing to participate in the study as indicated by signing the informed consent * Healthy post-menopausal women between the ages of 40 and 70 years, inclusive * Body mass index (BMI) less than or equal to 32 kg/m2 but greater than or equal to 19 kg/m2 * Judged by the Investigator to be healthy on the basis of medical evaluation Exclusion Criteria: * Hospitalized subjects * Symptoms of any significant acute illnesses at the screening visit * History of significant allergies (including food, asthma, or drug allergies including allergies to any ingredient of the trial product) * Known history of sensitivity to oxytocin or related derivatives * Follicle-stimulating hormone level \< 40 pmol/mL * Known history of narcotic addiction, drug abuse or alcoholism * Simultaneously participate in another clinical study * Use of any sex steroids including phytoestrogens, hormonal intrauterine device or herbal medicinal products with known estrogenic effects within 3 months prior to baseline * Uncontrolled hypertension and/or hypercholesterolemia