Potential biomarkers for obstructive sleep apnea (OSA), and full genomic screening will be evaluated and correlated to the degree of OSA and to effect of CPAP-treatment measured by polygraphy.
This project includes two parts: * Genomic screening * Biomarkers
Study Type
OBSERVATIONAL
Enrollment
75
Department of Anesthesiology, Surgical Sciences and Intensive Care Medicine, Karolinska University Hospital, Solna
Stockholm, Sweden
Biomarker
Biomarkers related to inflammation, hypoxia, oxidative stress, redox and the central nervous system will be measured
Time frame: Comparison between 0, 3 and 12 month
Genomics
Genomic screening by microarray
Time frame: Comparison between 0, 3, 12 month
Apnea hypopnea index
Apnea hypopnea index at 0, 3 and 12 month after treatment with CPAP in the obstructive sleep apnea groups
Time frame: Comparision between 0, 3 and 12 month
Exhaled nitric oxide
Measurement of exhaled nitric oxide
Time frame: Comparision at 0, 3 and 12 month
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