LDX and Functional Magnetic Resonance Imaging (fMRI in Menopausal Women

Inclusion Criteria: 1. Have no previous or present history of a DSM-IV psychiatric or substance dependence disorder within the previous year, according to the Structured Clinical Interview for Diagnosis- DSM-IV (SCID)-Non-Patient Version; 2. Are within 5 years of last menstrual period (LMP); 3. Have a follicular stimulating hormone level (FSH) of 20 IU/ml; 4. Are able to give written informed consent; 5. Must have clear urine toxicology screen upon recruitment; 6. Are fluent in written and spoken English; 7. Are right-handed; 8. Negative urine pregnancy test if still menstruating. Exclusion Criteria: 1. Mini-mental status exam score of less than or equal to 24; 2. Presence of a psychiatric disorder within previous year or a life time history of ADHD or psychotic disorder including bipolar disorder, schizoaffective disorder, and schizophrenia; 3. Lifetime history of drug addiction or abuse, except nicotine; 4. Regular use of other psychotropic medication; 5. Regular use (more than once a week) of alcohol that is less than 3 drinks/day; 6. Presence of a contraindication to treatment with stimulant medication unless the condition is controlled with medication; this would include the presence of uncontrolled hypertension, coronary disease, atrial fibrillation, and arrhythmia; 7. History of seizures; 8. History of cardiac disease including known cardiac defect or conduction abnormality; 9. Abnormal electrocardiogram during screening; 10. Use of estrogen therapy within previous 2 months; 11. Current pregnancy or planning to become pregnant; 12. Metallic implant; 13. Claustrophobia.