We propose to study a strategy empirically applied for the past 6 months at a high volume LVAD center (Vanderbilt Heart and Vascular Institute). This utilizes an ultra conservative device programming strategy to maximize battery longevity, avoid inappropriate implantable cardioverter defibrillator (ICD) therapy, improve quality of life through reduction in overall shock burden, and potentially avoid unnecessary device generator changes prior to transplant. Avoiding CIED (cardiac implantable electronic device) change out device procedures prior to transplant is desirable.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
HEALTH_SERVICES_RESEARCH
Masking
NONE
Enrollment
80
Vanderbilt University
Nashville, Tennessee, United States
Time to first ICD shock following LVAD implant
Time frame: Within 12 months following LVAD implant
Frequency of anti-tachycardia pacing (ATP) therapy administration for appropriate or inappropriate arrhythmia detection
Number of ATP occurrences
Time frame: Within 12 months following LVAD implant
Frequency of ICD generator change prior to definitive therapy
Number of patients requiring ICD generator change
Time frame: Within 12 months following LVAD implant
Cardiac implantable electronic device (CIED) battery voltage/estimated longevity changes
Battery voltage and battery life measured in days
Time frame: Within 12 months following LVAD implant
Frequency of arrhythmic syncope
Number of syncope occurrences
Time frame: Within 12 months following LVAD implant
Hospitalization frequency for decompensated congestive heart failure
Number of hospitalizations
Time frame: Within 12 months following LVAD implant
Determine survival to heart transplantation following LVAD implant
Number of patients, post LVAD implant, to receive heart transplant and number of survival days post implant
Time frame: Within 12 months following LVAD implant
This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.