Does Asthma Phenotype Have Impact on Disease Control

N/ACompletedNCT01978678

Bispebjerg Hospital80 enrolled

Overview

The application of biomarkers that are more closely associated with eosinophillic airway inflammation, such as measurements of FeNO level, cell count in induced sputum or bronchial reactivity could improve asthma control by better directing treatment. A systematic review and meta-analysis is to be conducted to assess the efficacy of tailoring asthma intervention on clinical symptoms compared with exhaled nitric oxide or induced sputum count.

AHR used as outcome

Study Type

OBSERVATIONAL

Enrollment

Conditions

Asthma

Interventions

PulmicortDRUG

ACQ and FeNO

Eligibility

Sex: ALLMin age: 15 YearsMax age: 100 Years

Medical Language ↔ Plain English

Inclusion Criteria: * positiv mannitol * asthma diagnose Exclusion Criteria: * other lung disease

Locations (2)

Department of Respiratory Medicine, L, Bispebjerg Hospital,

Copenhagen, NV, Denmark

Respiratory research unit, Bispebjerg University Hospital

Copenhagen, Denmark

Outcomes

Primary Outcomes

Control of asthma based on an algorithm

Based on ACQ and FeNO

Time frame: 2 years

Secondary Outcomes

The use of NO and sputum cell count as a marker in asthma management

Based on ACQ and FeNO

Time frame: 2 years

Data from ClinicalTrials.gov

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