Vascular Inflammation Stratified by Body Size Phenotype

N/ACompletedNCT01979068

Korea University250 enrolled

Overview

* Vascular Inflammation is a key factor in both the pathogenesis and outcome of atherosclerosis. 18FDG-PET is a promising novel tool for identifying and quantifying vascular inflammation within atherosclerotic plaque * Recently, unique subsets of obese individuals, such as metabolically obese but normal weight (MONW) and metabolically healthy obese (MHO), have been getting an attention * Therefore, the purpose of this study is to examine the relationship of vascular inflammation,measured by FDG-PET, with various body sized phenotypes

Study Type

OBSERVATIONAL

Enrollment

250

Conditions

Atherosclerosis Obesity Metabolic Syndrome

Eligibility

Sex: ALLMin age: 20 YearsMax age: 80 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * Healthy patients for visiting routine medical check in our clinic Exclusion Criteria: * history of CVD (myocardial infarction, unstable angina, stroke, or cardiovascular revascularization) * stage 2 hypertension (resting blood pressure, ≥160/100 mmHg) * history of inflammatory conditions that affect the study results * taking medications that might affect inflammatory status, including steroid and non-steroidal anti-inflammatory drug within 6 months * or malignancy or severe renal or hepatic disease

Locations (1)

Korea University Guro Hospital

Seoul, South Korea

Outcomes

Primary Outcomes

max TBR values stratified by the four body size phenotypes

Time frame: 12 weeks

Secondary Outcomes

Framingham risk scores according to the four body size phenotypes

Time frame: 12 weeks

Data from ClinicalTrials.gov

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