The Cognitive and Cardiovascular Health in the Elderly Study

N/ATerminatedNCT01979432

University Hospital, Limoges17 enrolled

Overview

The main objective of this study is to look for the interest forecast of the IPS as infra-clinical cardiovascular marker in the prediction of a change of the cognitive functions (MCI) at the elderly of 70 and more years old without clinical cardiovascular pathology.

Study Type

INTERVENTIONAL

Allocation

Purpose

DIAGNOSTIC

Enrollment

Conditions

Cognitive Diseases

Interventions

Cardiovascular evaluationOTHER

Eligibility

Sex: ALLMin age: 70 Years

Medical Language ↔ Plain English

Inclusion Criteria: * free-living community-dwelling men and women aged ≥ 70 years, * subjects free of clinical CVD related to atherosclerosis * preserved basic activities of daily living (ADL = 6) * without cognitive impairment (MMSE≥24) Exclusion Criteria: * subjects with clinical history of any of the following CVD diseases : coronary artery disease (angina, myocardial infarction, coronary revascularization), cerebrovascular disease (stroke, TIA, carotid revascularization), clinical peripheral artery disease (claudication, critical limb ischemia) * subjects with neurodegenerative, locomotor and ophtalmological diseases unable to perform the cognitive tests * subjects unable to give written informed consent.

Locations (1)

CHU of Limoges

Limoges, France

Outcomes

Primary Outcomes

Incident "MCI" according to the following criteria

(1) cognitive complaint (self-reported and/or informant) ; (2) preserved basic activities of daily living (ADL) ; (3) cognitive impairment (not normal for age and education) or decline in cognition evidenced by performance on objective cognitive tasks defined as a test performance \<1.0 standard deviations below the mean of the reference group ; (4) preserved general cognitive functioning and (5) absence of dementia.

Time frame: one time point

Data from ClinicalTrials.gov

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