Tai Chi Easy in Treating Cancer Survivors With Peripheral Sensory Neuropathy

N/AWithdrawnNCT01980368

Mayo Clinic

Overview

This pilot clinical trial studies how well Tai Chi Easy works in treating cancer survivors with peripheral sensory neuropathy. Tai Chi Easy is a simple and repetitive form of exercise that consists of movements with meditation and may improve peripheral neuropathy symptoms among cancer survivors.

PRIMARY OBJECTIVES: I. Examine effects of Tai Chi Easy (TCEasy) exercise intervention on peripheral sensory neuropathy of cancer survivors who have chemotherapy compared with an educational control (EC) intervention. OUTLINE: Patients are randomized to 1 of 2 groups. GROUP I (TAI CHI EASY): Patients attend Tai Chi Easy class for 60 minutes once a week for 6 weeks. Patients also receive a DVD and exercise manual of Tai Chi Easy exercises and are encouraged to practice at home for 30 minutes most days per week for 6 weeks. GROUP II (EDUCATIONAL CONTROL): Patients receive readings each week and attend a book club to discuss the readings for 60 minutes once a week for 6 weeks. After completion of study, patients are followed up at 2 months.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

SUPPORTIVE_CARE

Masking

NONE

Conditions

Cancer Survivor Peripheral Sensory Neuropathy

Interventions

Educational InterventionOTHER

Receive readings and attend book club

Exercise InterventionBEHAVIORAL

Receive Tai Chi Easy class, DVD, and exercise manual

Questionnaire AdministrationOTHER

Ancillary studies

Eligibility

Sex: ALLMin age: 18 Years

Medical Language ↔ Plain English

Inclusion Criteria: * 1 month - 5 years following completion of cytotoxic chemotherapy treatment for any cancer, and are experiencing neuropathy * Self-report of \>= 4 on the Peripheral Neuropathy Question Exclusion Criteria: * Recurrence of cancer or other active cancer * Severe cachexia, dizziness, bone pain, or severe nausea (as judged by the investigator) * Uncontrolled diabetes, untreated hypothyroidism

Outcomes

Primary Outcomes

Change in peripheral sensory neuropathy, assessed by Peripheral Neuropathy Question, European Organization for Research and Treatment of Cancer (EORTC)-30, EORTC-Chemotherapy-induced peripheral neuropathy-20, and the modified Total Neuropathy Score

Will be assessed with a simple t-test of mTNS means. Additional analyses of factors assessed will similarly be conducted (and overall analysis of variance when combining outcome variable assessment at the three time points, and models of factor contribution with logistic regression if appropriate).