Measurement of Neonatal Microvascular Hemodynamics Using Non-invasive Optical Technologies

N/ACompletedNCT01982357

University of California, Irvine32 enrolled

Overview

Alterations to microvascular blood flow in premature infants, are known to contribute to several major disease entities. The optically-measured tissue blood flow, to determine tissue perfusion that can be use to detect blood loss.

The researchers want to use optical technologies to non-invasively detect blood flow that can tell the onset of blood loss. The research can measure blood flow in stable premature infants in the Neonatal Intensive Care Unit over the duration of several weeks. The technologies are Laser Speckle Imaging and Diffuse Optical Spectroscopy. Laser Speckle Imaging non-contact imaging technology, is sensitive to blood flow in superficial tissues. Diffuse Optical Spectroscopy, a probe-based contact technology like pulse oximetry, measures hemoglobin concentrations and states deeper below the skin surface.

Study Type

OBSERVATIONAL

Enrollment

Conditions

Infant, Premature, Diseases

Interventions

Laser Speckle Imaging and Diffuse Optical SpectroscopyDEVICE

Laser Speckle Imaging and Diffuse Optical Spectroscopy

Eligibility

Sex: ALLMin age: 1 MinuteMax age: 1 MonthHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * premature infants born or transferred to neonatal intensive care unit with a gestational age of 28-35 weeks Exclusion Criteria: * NONE premature infants born or transferred to neonatal intensive care unit

Locations (1)

UCIMC

Orange, California, United States

Outcomes

Primary Outcomes

Normal Blood flow in premature infant

Time frame: up to 4 weeks

Data from ClinicalTrials.gov

This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.