The purpose of this study is to observe the persistence of protection, duration of protection, safety and breakthrough infection rates afforded by live attenuated varicella vaccine in children over a 5-year period.
Study Type
INTERVENTIONAL
Allocation
NA
Purpose
PREVENTION
Masking
NONE
Enrollment
350
Maoming Center for Disease Control and Prevention
Maoming, Guangdong, China
Immune protective effect and persistence after inoculated with live attenuated varicella vaccine
Clinical subjects are drawn 3ml's vein blood,respectively before vaccination, six weeks and every year in 5 years study period after inoculation of the live varicella vaccine. FAMA methods are used to test antibody rate of pox virus.
Time frame: Before vaccination, six weeks and every year in 5 years study period after inoculation of the live varicella vaccine
Breakthrough rate, duration and severity of varicella in vaccinated children
Time frame: 5 years period
Occurrence of adverse events
Time frame: Up to 4 weeks after vaccination
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