Diagnostic Accuracy of Ferumoxytol-Enhanced MRI for Detecting Lymph Node Metastases in Colorectal Cancer

Inclusion Criteria: * Patients 18 years of age or older with histologically confirmed colorectal cancer * Planned for surgical resection of tumor Exclusion Criteria: * Contraindications for MRI * Contraindication or known allergy to ferumoxytol or parental iron products (e.g. iron sucrose, iron dextran, etc.) * Planned chemotherapy or radiation treatment prior to surgical resection of primary tumor * Uncontrolled serious medical illness * Unable or unwilling to give informed consent * Pregnancy * Breastfeeding women * Clinically documented or known risk of primary or secondary iron overloading including history of thalassemia, sickle cell anemia, hereditary hemochromatosis or first-degree relative with known hemochromatosis, multiple transfusions for any reason within the past 5 years, or use of over-the-counter ferrous sulfate without the supervision of his/her doctor