RESEARCH HYPOTHESIS -Incidence of preterm delivery is lower in women treated with oral micronized progesterone (Utrogestan) as acute tocolysis agent compare to Nifedipine group with fewer maternal side effect
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
PREVENTION
Masking
SINGLE
Enrollment
32
Oral Tablet Utrogestan 400 mg daily for 2 days
Tablet Nifedipine 20 mg stat then 20 mg after 30 minutes if contraction persist and another 20mg after 30 minutes if contraction still persist followed by 10 mg three times daily for 2 days
Obstetric and Gynaecology Department, National University of Malaysia Medical Centre
Cheras, Kuala Lumpur, Malaysia
latency period interval between time of tocolysis and delivery
delivery less than 24 hours of tocolysis,delivery less than 48 hours of tocolysis, delivery less than 7 days of tocolysis
Time frame: 24 hours up to 7 days
Pregnancy outcomes
delivery less than 34 weeks of gestation, delivery more than or at 34 weeks of gestation
Time frame: 34 weeks of gestational age
Neonatal outcome
Birth weight (kg),cord blood acidity, need for neonatal intensive care unit admission
Time frame: 24 hours
Maternal side effect
Palpitation,Headache, Nausea/Vomiting, Hypotension, Dyspnea, Jaundice, Pruritus
Time frame: 30 minutes up to 48 hours
This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.