Transversus Abdominis Plane (TAP) Block for Post Caesarian Pain

Phase 3WithdrawnNCT01986049

New York Presbyterian Brooklyn Methodist Hospital

Overview

Adding TAP block with Bupivacaine may decrease the use of PCA bolus use after caesarean section for pain relief.

Participants in the study will be randomized to TAP block with 0.5% or 0.25% bupivacaine or with placebo (normal saline). The number of PCA bolus used within 24 hours post cesarean section will be compared between the groups.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

QUADRUPLE

Conditions

Obstetrical Complications From Sedation During Parturition

Interventions

BupivicaineDRUG

Eligibility

Sex: FEMALEMin age: 18 YearsMax age: 50 Years

Medical Language ↔ Plain English

Inclusion Criteria: Healthy pregnant (ASA II) patients presenting for planned Cesarean delivery at New York Methodist Hospital under combined spinal epidural anesthesia Exclusion Criteria: * They are unable or are unwilling to take part in the study * They have a history of allergy to any of the medications to be used in the study * They have a history of drug abuse or chronic pain or opioid use * They weigh less than 60kg * They have a multiple gestation, placental disease, preeclampsia other disease of pregnancy * They have a contraindication to neuraxial anesthesia (i.e., bleeding problems, bacteremia, etc.) * They are unable to understand instructions or questions related to the study * ASA III or IV

Locations (1)

New Yoyk Methodist Hospital

Brooklyn, New York, United States

Outcomes

Primary Outcomes

Transversus Abdominis Plane (TAP) Block for Post Caesarean Pain

In Patient Controlled analgesia (PCA) system, the patient receives a preset dose of morphine by pressing a button on a computerized pump that is connected to an IV catheter. With PCA the patient may receive a small continuous flow of morphine and add more morphine as needed to provide a more constant level of comfort. In this study, we will compare the number of PCAs used by the participants in each arm

Time frame: The first post operative 24 hours

Secondary Outcomes

Decrease in the pain score as measured by Visual Analog Scale (VAS)

Visual Analog Scale (VAS) is a numeric scale to measure the pain intensity from 0 to 10, where 0 = no pain, (1-3) = mild pain, (4-6) = moderate pain, and (7-10) = severe pain. The worst imaginable pain = 10

Time frame: The first post operative 24 hours

Data from ClinicalTrials.gov

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