Effect of Timing of a Post-exercise Oral Glucose Tolerance Test on Glycaemic Control.

N/ASuspendedNCT01987687

Northumbria University12 enrolled

Overview

Postprandial glycaemic control is an important risk factor for the development of type 2 diabetes, cardiovascular disease and all-cause mortality. Previous research has demonstrated that exercise performed in the postprandial state paradoxically results in a deterioration in glucose tolerance in the immediate post-exercise period (Gonzalez et a. 2013; Gonzalez and Stevenson 2013). This study aims to assess the timecourse of this post-exercise effect.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

BASIC_SCIENCE

Masking

NONE

Enrollment

Conditions

Area Under Curve [N06.850.520.830.200]

Interventions

ExerciseBEHAVIORAL

Exercise at 55% of maximum power output for 30 min.

RestBEHAVIORAL

Rest for 30 min

DelayBEHAVIORAL

Delay between exercise and OGTT

Eligibility

Sex: MALEMin age: 18 YearsMax age: 40 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * Normal weight (18-25 kg/m2) * Physically active (\>or= 3 times per week) * Male Exclusion Criteria: * Contraindications to exercise * Food intolerances * Food allergies

Locations (1)

Northumbria University

Newcastle upon Tyne, Tyne and Wear, United Kingdom

Outcomes

Primary Outcomes

Postprandial glucose concentration area under the curve

Blood glucose concentrations will be sampled every 15 min following an oral glucose tolerance test.

Time frame: 90 min

Secondary Outcomes

Postprandial insulin concentration area under the curve

Insulin concentrations will be determine every 15 min following an oral glucose tolerance test.

Time frame: 90 min

Data from ClinicalTrials.gov

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