Can oral midazolam used for sedation in patients undergoing upper gastrointestinal endoscopy ?
Five mg of midazolam was intake orally about 30 minutes before undergoing perform upper gastrointestinal endoscopy. Declined of anxiety scores was primary end point.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
DOUBLE
Enrollment
260
5 mg in 15 mL of apple juice, orally 30 minutes before undergoing EGD
Division of Gastroenterology, Department of Medicine, Phramongkutklao hospital
Bangkok, Thailand
RECRUITINGDifference of Anxiety score
* Anxiety score is 10-cm scaled visual analog scale. * Anxiety score which asked the patient 5 minutes before EGD, called "Pre EGD anxiety score" * Anxiety score which asked the patient after fully recovery, called "During EGD anxiety score". * Difference of anxiety score means "Pre EGD minus During anxiety score". * Fully recovery means fully gain of consiouness (time, place, person).
Time frame: Asked the patient 5 minutes before EGD and then after fully recovery from sedation.
Overall tolerance
Fully recovery means fully gain of consiouness (time, place, person). Overall tolerance was grading into 4 levels; * Poor : Very uncomfortable during the entire procedure * Fair : Uncomfortable during most of the procedure * Good : Believes the procedure was generally comfortable, there were portions of procedure during which sedation could have been given * Excellent : Believes the procedure was comfortable, no additional sedation was needed
Time frame: Asked the patient after fully recovery from sedation.
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