IVIG Treatment for Asthmatic Patients With IgG Subclass Deficiency

Inclusion Criteria: * The patient from over 16 years to under 75 years * Patients diagnosed with asthma over six months ago * immunoglobulin G subtypes who were diagnosed with immune deficiency * more than 2 years Upper and lower respiratory tract infections , and asthma exacerbations in this regard. * ① calculated creatinine clearance ≧ 50ml/min * ALT and AST \<x 3 times the upper limit of normal * ALP \<x 3 times the upper limit of normal * total bilirubin \<x 1.5 times the upper limit of normal Exclusion Criteria: * within six months of the onset of the experiment who received immunoglobulin therapy * immune globulin for those with a history of hypersensitivity reactions * six months ago, another clinical trial participants. * Systemic steroids and immunomodulators, such as asthma control that may affect the resources required drug administration. * pregnant or lactating women.