The principal study aims at evaluating the efficiency of rTMS maintenance sessions on the clinical effect of a rTMS cure in fibromyalgic subjects. This complementary study consists in the evaluation of the experimental sensitivity to mechanical pain (pressure application on the forearm) of subjects presenting fibromyalgia before and after rTMS treatment (21 days), and to put the results in relation to the clinical improvement and the psychometric evaluations (depression,fibromyalgia impact questionnaire, catastrophism).
Study Type
INTERVENTIONAL
Allocation
NA
Purpose
OTHER
Masking
NONE
Enrollment
72
application of a pre-fixed pressure (160 kPa) on the forearm.
Centre Hospitalier esquirol
Limoges, France
Variation in the Visual Analogic Scale (VAS)score after fixe pressure application (160 kPa) between the first rTMS session (T0) and the last rTMS session (T21)in relation to clinical improvement
The clinical improvement is defined as : 30% decrease in the general painful state evaluated by VAS between T0 and T21 and response to the Patient's Global Impression of Change ≥ 6 at T21
Time frame: 21 days
variation in the experimental pain feeling (VAS) between T0 and T21 in relation to treatment group
Time frame: 21 days
variation in experimental pain feeling between T0 and T210 (the end of rTMS maintenance sessions)
Time frame: 210 days
variation in Beck Depression Inventory scores between T0 and T21
Time frame: 21 days
variation in Fibromyalgia Impact Questionnaire score between T0 and T21
Time frame: 21 days
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