The purpose of this study is to retrieve and cryopreserve ovarian tissue from females undergoing a treatment that may lead to irreversible loss of ovarian function.
The aim of this preliminary study is to retrieve and properly cryopreserve ovarian tissue for autotransplantation in any premenopausal female whose ovarian function is threatened in a physiological, pathological or iatrogenic manner in an effort to observe the return of ovarian endocrine function and development of egg(s) appropriate for use in in vitro fertilization.
Study Type
INTERVENTIONAL
Allocation
NA
Purpose
PREVENTION
Masking
NONE
Enrollment
15
Females undergoing therapeutic procedures that will potentially lead to the irreversible loss of ovarian function will have their ovarian tissue retrieved and cryopreserved. Ideally, after treatment, the cryopreserved ovarian tissue can be thawed and auto-transplanted and ovarian function resumed.
Children's Hospital of Wisconsin
Milwaukee, Wisconsin, United States
Froedtert and The Medical College of Wisconsin
Milwaukee, Wisconsin, United States
Return of hormones produced by the ovarian tissue
Time frame: 3 months after re-implantation
Development of egg(s) appropriate for use in in vitro fertilization
Time frame: Participants will be followed through their reproductive years (until the patient reaches 45 years of age)
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