Prevalence of MTHFR Polymorphisms in Venous Disease

N/ACompletedNCT01993914

Health Diagnostic Laboratory, Inc.90 enrolled

Overview

The etiologies of varicose veins and the progression to more serious forms of chronic venous disease and identification of appropriate diagnostic tests to better aid patient management by identifying individuals who may benefit from more aggressive treatment and/ or prophylactic measures.

Study Type

OBSERVATIONAL

Enrollment

Conditions

Varicose Veins MTHFR Venous Disease Thrombosis

Eligibility

Sex: ALLMin age: 18 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * Age 18 or over * No venous disease (N=30); or C2-C3 venous disease (N=30); or C4-C6 venous disease (N=30) Exclusion Criteria: * Pregnancy * Cancer * Chronic obstructive pulmonary disease (COPD) * Any systemic inflammatory disease * Any of the following within the previous 30 days: * Trauma * Any surgery * Periods of prolonged inactivity

Locations (1)

The Elite Laser Vein Center

Los Angeles, California, United States

Outcomes

Primary Outcomes

Prevalence of MTHFR mutation between patients

Determine whether the prevalence of the MTHFR mutation differs between patient with varicose veins compared to controls and with or without superficial vein thrombosis.

Time frame: Baseline

Data from ClinicalTrials.gov

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