Polycystic ovary syndrome (PCOS) is a common endocrine disorder in premenopausal women. Women with PCOS often have problems with fertility, unwanted hair growth, and irregular menstrual cycle. PCOS is associated with obesity, changes in glucose metabolism and low quality of life. In the present study, hormonal profile, glucose metabolism, adrenal functon, androgen levels, cortisol metabolism, anflammatory response, ovarian morphology, body composition, pfysical activity and quality of life is studied in 40 healthy women. The results will be compared with results from studies on women with PCOS in order to investigate any differences in these parametres.
Study Type
OBSERVATIONAL
Enrollment
40
Odense University Hospital
Odense, Denmark
Level of androgens
Level of testosterone and sexual hormone binding globuline in blood samples
Time frame: baseline
Quality of life
Quality of life measured by validated questionnaires
Time frame: Baseline
Body composition
Body composition measured by full body DXA-scan with estimates on lean body mass and fat mass
Time frame: baseline
Bone density
Bone density measured by DXA scan of hip and wrist
Time frame: baseline
Glucose tolerance
Glucose tolerance measured by 5 hour oral glucose tolerance test with blood glucose measurements for 5 hours after oral intake of 75 g glucose
Time frame: 5 hours
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