Early NCPAP Before Surfactant Treatment in Very Preterm Infants With RDS

N/ACompletedNCT01996670

Xiangya Hospital of Central South University683 enrolled

Overview

We hypothesis a period of early NCPAP before surfactant treatment is effective for treating RDS and preventing BPD in very premature infants.

Study Type

OBSERVATIONAL

Enrollment

683

Conditions

Nasal Continuous Positive Airway Pressure,Preterm Infants,Surfactant Treatment,Respiratory Distress Syndrome,Bronchopulmonary Dysplasia

Eligibility

Sex: ALLMin age: 30 MinutesMax age: 2 Hours

Medical Language ↔ Plain English

Inclusion Criteria: * All enrolled infants were able to breathe at 5 min of age, had evidence of respiratory distress, unable to receive surfactant therapy, and were administrated with early NCPAP as the initial treatment Exclusion Criteria: * Exclusion criteria were endotracheal intubation for resuscitation or insufficient respiratory drive, died in the first 24 hours after birth, known genetic disorders, potentially life-threatening conditions unrelated to prematurity, and premature rupture of membranes (PROM) for \>3 weeks.

Outcomes

Primary Outcomes

death or bronchopulmonary dysplasia

Time frame: 24 hours after birth

Data from ClinicalTrials.gov

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