Prospective Trial of Tranexamic Acid in Cardiac Surgery

Inclusion Criteria: * Noncyanotic congenital heart disease patients requiring cardiac surgeries under cardiopulmonary bypass * Rheumatic or recessive valvular disease patients requiring valvular repair or replacement under cardiopulmonary bypass * Coronary artery disease patients requiring coronary artery bypass graft under cardiopulmonary bypass Exclusion Criteria: * Non-primary and emergency cardiac surgery * Disorder in coagulation function before surgery * Anemia before surgery * Definite liver and renal dysfunction * History of stroke * Pregnancy and lactation * Disabled in spirit or law * Fatal conditions such as cancer