We found a new Double sphincter which located in the neck of gallbladder,we supposed it may be related to control pressure of bile duct.Its formation is related to genetic factors.
To contrast the recurrence rate of gallstones between patients with gallbladder double sphincter and patients with general gallbladder sphincter who underwent the treatment of cholecystolithiasis by minimally invasive cholecystolithotomy with gallbladder reservation. Method:Patients with gallbladder double sphincter and patients with general gallbladder sphincter who underwent the treatment of cholecystolithiasis by minimally invasive cholecystolithotomy with gallbladder reservation in The Affiliated Hospital of Guiyang Medical College from May 2012 to December 2015. We collect these patients' bile during surgery.Patients with gallbladder double sphincter as trial group, patients with general gallbladder sphincter as control group.the overall follow-up period is 3 years. Then the investigators statistically analyze improvement of cholecystolithiasis symptoms, thickness of gall bladder wall, the gallbladder function and the rate of the recurrence of cholesterol gallstone in 2 groups.we also analysis of the genetic differences from bile between two groups.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
PREVENTION
Masking
SINGLE
Enrollment
150
patients from double sphincter group and general gallbladder sphincter group all received Tauroursodeoxycholic acid after surgery for 6 months.
The Discovery of the Double Sphincter in Gallbladder
Guiyang, Guizhou, China
RECRUITINGThe Discovery of The Double Sphincter in Gallbladder
The gallbladder of some gallstone patients contain a new Anatomical structure named Double sphincter which located in the middle of gallbladder,we supposed it may be related to the formation of gallstone and pressure of bile duct.Its formation is related to genetic factors.
Time frame: All the patients will be follow-up for an expected average of 3 years.
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