The Intraocular Pressure Measured by Different Tonometers in Corneal Edema

N/ACompletedNCT01998568

Prince of Songkla University50 enrolled

Overview

The investigators conduct this study to access the effect of corneal edema (the investigators are particularly interested in those who have the clinical central corneal edema) on the variation of intraocular pressure values measured by 3 commercial-available tonometers compare to the current gold standard tonometer; Goldmann applanation tonometer.

Previous published articles reported on the effect of corneal edema on the accuracy of tonometry were performed in enucleated cadaver eyes, or contact lens-induced corneal edema eyes. Thus, it remains unclear as to how the clinical corneal edema that is found in routine clinical practice will affect the variation of intraocular pressure measurement using the standard Goldmann applanation tonometer and other more modern tonometers such as the dynamic contour tonometer, the iCare, and the Tonopen.

Study Type

OBSERVATIONAL

Enrollment

Conditions

Intraocular Pressure Corneal Edema

Interventions

Intraocular pressure measurementOTHER

Using different tonometers for intraocular pressure measurement

Eligibility

Sex: ALLMin age: 18 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Age more than 18 year-old * Patients who have a clinical central corneal edema after clear cornea phacoemulsification and intraocular lens implantation * Agree to participate in the study and willing to sign an informed consent Exclusion Criteria: * Combined phacoemulsification and trabeculectomy * Clear cornea phacoemulsification that has suture on the cornea * Previous history of intraocular surgery, ocular trauma prior to phacoemulsification * Vitrectomized eye * History of glaucoma or ocular hypertension or using IOP lowering medication * History of diabetic retinopathy staged as severe non-proliferative or worse * Pregnant or breast-feeding women * History of refractive surgery or any keratoplastic procedure * Corneal opacities or diseases making no suitable tonometry * Severe dry eye syndrome * Wears contact lenses * Astigmatism higher than 2.5 diopters * Microphthalmos or buphthalmos * Subjects with having poor or eccentric fixation or nystagmus * Excessive eye squeezing * Known allergy to topical anesthesia * Known allergy to fluorescein solution

Locations (1)

Faculty of Medicine, Prince of Songkla University

Hat Yai, Changwat Songkhla, Thailand

Outcomes

Primary Outcomes

Intraocular pressure

The intraocular pressure measured by each tonometer compare with Goldmann applanation tonometer (When measure in eyes with corneal edema and when the edema is clinically resolve)

Time frame: A day after cataract surgery and when the corneal edema is resolve (usually within 1-2 weeks post operatively)

Secondary Outcomes

Relationship between the central corneal thickness and intraocular pressure measured by each tonometer

The severity of corneal edema may affect the reliability of intraocular pressure measurement measured by different tonometers

Time frame: A day after surgery (clinical corneal edema was detected) and within 1-2 weeks (resolution of edema)

Data from ClinicalTrials.gov

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