Phase 3 Study of EBI-005 in Dry Eye Disease

Inclusion Criteria: * Give written informed consent and any authorizations required by local law (e.g., Protected Health Information waiver) prior to performing any study procedures; * Are ≥ 18 years of age; * Are willing and able to follow instructions and can be present for the required study visits for the duration of the study; * Have a history of dry eye disease (DED) in both eyes supported by a previous clinical diagnosis * Have normal lid anatomy. * If female and of child bearing potential, she must not be not pregnant or lactating and not sexually active (abstinent) within 14 days prior to Visit 1 Exclusion Criteria: * Have signs of infection (i.e., fever or current treatment with antibiotics) * Have been exposed to an investigational drug/device within the preceding 30 days * Be an employee of the site that is directly involved in the management, administration, or support of the study, or be an immediate family member of the same * Be unwilling to or unable to comply with the study