The effects of two palaeolithic-type meals will be assessed with respect to a panel of gut hormones, satiety, blood glucose and insulin levels as compared to a meal constructed along the lines of the world Health Organisation dietary recommendations
In the current study the effects of two palaeolithic-type meals will be assessed with respect to a panel of gut hormones (including incretins), satiety, blood glucose and insulin levels.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
PREVENTION
Masking
DOUBLE
Enrollment
24
Leatherhead Food Research
Leatherhead, Surrey, United Kingdom
Glucagon-like peptide-1
Area under the Concentration versus time curve for Glucagon-like peptide-1 in blood plasma
Time frame: 0-3 hours
Glucose-dependent Insulinotropic Peptide
Area under the Concentration versus time curve of Glucose-dependent Insulinotropic Peptide in blood plasma
Time frame: 0-3 hours
Fullness
Area under the curve for fullness scores (as rated by the subjects on a Visual Analog Scale) versus time
Time frame: 0-4 hours
Glucose
Area under the Concentration versus time curve of Glucose in blood
Time frame: 0-3 hours
Insulin
Area under the Concentration versus time curve of insulin in blood plasma
Time frame: 0-3 hours
Glucagon
Area under the Concentration versus time curve of Glucagon in blood plasma
Time frame: 0-3 hours
Peptide YY
Area under the Concentration versus time curve of Peptide YY in blood plasma
Time frame: 0-3 hours
Hunger
Area under the curve for hunger scores (as rated by the subjects on a Visual Analog Scale) versus time
Time frame: 0-4 hours
Desire to eat
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Area under the curve for desire to eat scores (as rated by the subjects on a Visual Analog Scale) versus time
Time frame: 0-4 hours