Vascular Function on the First Day After Cardiac Surgery

N/ACompletedNCT02001090

Norwegian University of Science and Technology25 enrolled

Overview

This study examines the flow mediated dilation (FMD) of the brachial artery before and after cardiac surgery. FMD is measured with ultrasound technique. Increased flow is achieved trough obstructing blood flow with a cuff around the forearm for five minutes. FMD is measured before surgery and on the first morning after the operation.

Study Type

OBSERVATIONAL

Enrollment

Conditions

Coronary Artery Disease

Eligibility

Sex: ALLMin age: 30 Years

Medical Language ↔ Plain English

Inclusion Criteria: * admitted for coronary artery bypass surgery Exclusion Criteria: * Ongoing treatment with nitrates or RAAS inhibiting drugs * unstable coronary syndrome * unstable circulation/shock * renal failure * hepatic failure * autoimmune or inflammatory disease * untreated hypertension.

Locations (1)

St. Olavs Hospital

Trondheim, Sør Trøndelag, Norway

Outcomes

Primary Outcomes

flow mediated dilation of the brachial artery

Transitory change in FMD as a consequence of cardiac surgery with use of extra corporal circulation.

Time frame: one day

Secondary Outcomes

Reactive hyperemia

Transitory change in reactive hyperemia after five minutes of occlusion of forearm blood flow as a consequence of cardiac surgery with the use of extra corporal circulation.

Time frame: one day

Data from ClinicalTrials.gov

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