Remifentanil and Nitroprusside for Controlled Hypotension

N/ACompletedNCT02001298

Jeju National University School of Medicine30 enrolled

Overview

The purpose of this study is the comparison of the cardiovascular effects of remifentanil and nitroprusside for controlled hypotension

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Masking

NONE

Enrollment

Conditions

Hypotension, Controlled

Interventions

remifentanilDRUG

nitroprussideDRUG

Eligibility

Sex: ALLMin age: 20 YearsMax age: 60 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Patients who underwent endoscopic sinus surgery Exclusion Criteria: * patient who took any drug to influence this study * patient with cardiovascular disease, renal disease or liver disease

Locations (1)

Jeju National University Hospital

Jeju City, Jeju Special Self-Governing Province, South Korea

Outcomes

Primary Outcomes

Cardiac index

Cardiac index was continuously measured during controlled hypotension using noninvasive cardiac output monitor. The average of cardiac index during controlled hypotension was compared with baseline value.

Time frame: Cardiac index was continuously measured during controlled hypotension, an average of 90 min

Secondary Outcomes

Total peripheral resistance index

Total peripheral resistance index was continuously measured during controlled hypotension using noninvasive cardiac output monitor. The average of total peripheral resistance index during controlled hypotension was compared with baseline value.

Time frame: Total peripheral resistance index was continuously measured during controlled hypotension, an average of 90 min

Data from ClinicalTrials.gov

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