REal World Information on Cardiovascular Drug Management Patterns in Acute Coronary Syndrome paTients

N/ACompletedNCT02001545

AstraZeneca814 enrolled

Overview

RE-ACT is a national, multi-centre, observational, prospective, longitudinal cohort study which will include patients hospitalized for ACS within 24 hours of symptom onset and who have a final diagnosis of ST-segment elevation myocardial infarction (STEMI) or non-ST-segment elevation myocardial infarction (NSTEMI). This study aims to describe the short-term (at the end of the first month after index event) antithrombotic management patterns in a "real-life" setting for patients hospitalized with an acute coronary syndrome.

Study Type

OBSERVATIONAL

Enrollment

814

Conditions

Acute Coronary Syndrome

Eligibility

Sex: ALLMin age: 18 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Provision of subject informed consent * Patients hospitalized and diagnosed with STEMI or NSTEMI * Hospitalized within 24 hours of onset of symptoms or transferred from another hospital within 24 hours of the onset of symptoms Exclusion Criteria: * STEMI and NSTEMI precipitated by or as a complication of surgery, trauma, or GI bleeding or post-PCI. * STEMI and NSTEMI occurring in patients already hospitalized for other reasons. * Presence of any condition/circumstance which in the opinion of the investigator could significantly limit the complete follow up of the patient (e.g. tourist, non-native speaker or does not understand the local language, psychiatric disturbances).

Locations (8)

Research Site

Blagoevgrad, Bulgaria

Research Site

Burgas, Bulgaria

Research Site

Lovech, Bulgaria

Research Site

Plovdiv, Bulgaria

Outcomes

Primary Outcomes

Short-term antithrombotic management patterns (AMPs) in a real-life setting for patients hospitalized with an ACS

Descriptive statistics will be calculated for this outcome measure using frequency tables (n, frequency and percentage). Antithrombotic management patterns will be grouped taking into account only the different treatment options shown by the descriptive analysis.

Time frame: Baseline

Secondary Outcomes

Variations in the acute clinical management strategies and AMPs.

Descriptive statistics will be calculated for this outcome measure using frequency tables (n, frequency and percentage).

Time frame: Baseline

Impact of the different AMPs on quality of life at discharge from hospital (using EuroQoL-5D).

Descriptive statistics will be calculated for this outcome measure using frequency tables (n, mean, median, standard deviation, minimum and maximum)

Time frame: Baseline

Impact of the different AMPs on quality of life at the end of the first month after discharge from the hospital (using EuroQoL-5D).

Descriptive statistics will be calculated for this outcome measure using frequency tables (n, mean, median, standard deviation, minimum and maximum)

Time frame: At the end of the first month after index event

Determinants of AMP choices (i.e. patient's characteristics, hospital characteristics, coronary intervention strategies and type of coronary stents used)

Descriptive statistics will be calculated for this outcome measure using frequency tables (n, frequency and percentage).

Time frame: Baseline

Data from ClinicalTrials.gov

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