Drug-drug Interaction Study(Lobeglitazone, Warfarin)

Inclusion Criteria: * A healthy male volunteer between 19 and 55 years old. * BMI between 19 and 27. * Signed the informed consent form prior to study participation. * Able to participate in the entire trial Exclusion Criteria: * Clinically significant hepatic, renal, digestive system, respiratory system, endocrine system, nervous system, hematologic, cardiovascular system, tumor or have history of tumor * Clinically significant hemorrhagic disease * Genetic problems such as galactose intolerance, Lapp lactase deficiency, glucose-galactose malabsorption * Have hypersensitivity reactions history for lobeglitazone, warfarin, excipient of IP or aspirin, antibiotics * Medication which might significantly alter the absorption, distribution, metabolism, or excretion of investigational products within 30 days prior to screening * Participated in the other clinical trials and administrated IP within 60 days prior to screening * Subject takes ethical drug or herbal medicine within 14 days, OTC within 7 days before screening * Previously donate whole blood within 60 days or component blood within 30 days * sit SBP \< 90mmHg or sit SBP ≥ 140mmHg or sit DBP \< 60mmHg or sit DBP ≥ 90mmHg * A heavy alcohol consumer (alcohol \> 140 g/week) or cannot stop drinking * A heavy smoker (cigarette \> 10 cigarettes per day) or cannot stop smoking * A heavy caffeine consumer (more than 4cups per a day) or A heavy grapefruit consumer (more than 1cup per a day) or cannot stop having * Positive for the Triage TOX drug on urine * Positive for HIV antibody, HBsAg, HCV antibody test * AST, ALT or Total bilirubin \> UNL \* 1.5 * Estimated GFR \< normal limit * INR, aPTT over the normal limit * Clinically significant laboratory test result * Clinically significant ECG * An impossible one who participates in clinical trial by investigator's decision including other reason