Surgery Plus Celiac Nerve Block for Long-term Pancreatic Cancer Pain Control

Inclusion Criteria: This study will be offered to all patients scheduled to undergo open or laparoscopic operative resection of a presumed pancreatic (any location; i.e., head, body, or tail) or distal biliary tract cancer. * Physiologic suitability for major abdominal surgery * Aged 18 years and older * Written informed consent * Ability to understand and comply with study guidelines. Exclusion Criteria: * Pregnancy * Previous, preoperative celiac nerve block * Neoadjuvant chemotherapy or radiation therapy * Incomplete tumor resection (R2 resection, grossly positive resection margin) * Presumed ampullary or duodenal cancer based on preoperative work-up or intraoperative findings * Benign tumors, neuroendocrine tumors, soft tissue tumors based on preoperative work-up or intraoperative findings * Known metastatic disease