Electronic cigarettes have shown promise but have yet to proven effective for smoking cessation. This trial will evaluate the effectiveness of electronic cigarettes in smokers who are trying to quit smoking compared with a standard therapy, the nicotine inhaler. The investigators hypothesize that electronic cigarettes will be comparable to the nicotine inhaler in terms of smoking cessation.
Cigarette smoking remains the leading cause of preventable death and disease worldwide. The purpose of this trial is to evaluate the effectiveness of electronic cigarettes for smoking cessation compared to a similar nicotine replacement therapy, the nicotine inhaler.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
NONE
V2 Cigs with 24 mg nicotine cartridges
nicotine inhaler with 10 mg nicotine cartridges
Substance Treatment and Research Services (STARS)
New York, New York, United States
Cigarettes smoked over 24 hours
Time frame: 4 weeks
Symptoms of nicotine withdrawal
We will measure the incidence and severity of nicotine withdrawal symptoms, including irritability, anxiety, depressed mood and increased appetite.
Time frame: 4 weeks
Benefits from smoking cessation
we will measure perceived benefits from smoking cessation including improved breathing, improved sense of taste and smell, and improved physical fitness.
Time frame: 4 weeks
Adverse reaction to nicotine inhaler or electronic cigarette
we will assess for any possible side effect from the electronic cigarette or the nicotine inhaler, including irritation of the mouth and throat and cough.
Time frame: 4 weeks
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