In France the prevalence of pre-lingual deafness is between 1 and 1.4 per 1000 habitants, and according to very conservative estimates, about 44 000 deaf persons use the sign language. Additionally, the prevalence of dementia in France is close to 1% (850 000 dements for a total population of 65 millions). The prevalence of dementia in pre-lingual deaf adults has also been described and is between 1 and 1.4 /100 000 habitants. The Mini Mental State Examination (MMSE) of Folstein is a test recommended to perform the cognitive evaluation for the detection of mental disorders including dementia, and a consensual French version exists prepared by GRECO (Group of Research and Cognitive Assessments). However, to date, there are no simple, rapid and validated screening tests to study cognitive disorders in deaf persons who use the sign language. The only tests available allow a late diagnosis avoiding an optimal treatment of the patients.
The objective of this study is to assess the intrinsic quality of the tool MMS-LS, a mini-mental state examination that has been adapted to the sign language in order to monitor cognitive disorders in deaf people who speak sign language.
Study Type
INTERVENTIONAL
Allocation
NA
Purpose
DIAGNOSTIC
Masking
NONE
Enrollment
195
Hôpital de la Conception, Pôle psychiatrie Centre
Marseille, Bouches-du-Rhône, France
Groupement des Hôpitaux de l'Institut Catholique de Lille
Lille, Hauts-de-France, France
CHU de Rennes, Hôpital de Pontchaillou
Rennes, Ille-et-Vilaine, France
Unité Régionale d'Accueil et de Soins pour Sourds et malentendants - CHRU Nancy
Nancy, Meurthe-et-Moselle, France
Assessment of internal consistency of MMS-LS test for the diagnosis of cognitive impairment among deaf patients by a correlation analysis followed by Cronbach's alpha test
Time frame: At baseline, 1 year and 2 years follow-up visits
Description of MMS-LS test results
Explanatory Factors are: age, education level, characteristics of the sign language(fluency level, learning age, usage frequency, usage by other family members)
Time frame: Baseline
Diagnostic performance and predictive values of MMS-LS test for acquired dementia.
Sensitivity, specificity, positive and negative predictive values.
Time frame: Baseline, 1 year and 2 years follow-up visits
Correlation between MMS-LS score and CDR level
We also check that patients having a suspicious CDR (0.5) have a superior MMS-LS score compared to patients having a CDR ≥ 1.
Time frame: Baseline, 1 year and 2 years follow-up visits
Diagnostic performance and predictive values of MMS-LS test for suspected dementia.
Sensitivity, specificity, positive and negative predictive values
Time frame: Baseline, 1 year and 2 years follow-up visits
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