The purpose of is to determine the preventive effects of Chinese herb supplement with panax ginseng and salvia miltiorrhiza prior to eccentric resistance exercise on arterial stiffness and vascular reactivity by using a double-blind randomized control design and to examine the effects of a 12-week progressive eccentric resistance exercise training on arterial elasticity and vascular reactivity, and whether a long-term supplementation would ameliorate arterial stiffening effects elicited by exercise-induced inflammation and improve endothelial function.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
QUADRUPLE
Enrollment
48
12 weeks of lower leg eccentric training
National Taiwan University
Taipei, Taiwan
RECRUITINGPulse Wave Velocity
PWV will be measured before, 6th week, 12th week of eccentric exercise training.
Time frame: Before eccentric exercise and training
Pulse Wave Velocity
PWV will be measured before, 6th week, 12th week of eccentric exercise training.
Time frame: 6th week of eccentric exercise traininig
Pulse Wave Velocity
PWV will be measured before, 6th week, 12th week of eccentric exercise training.
Time frame: 12th week of eccentric exercise training
Blood pressure
Morning blood pressure will be measured before, during, and after 12 week of dietary and eccentric exercise intervention.
Time frame: Before intervention
Blood pressure
Morning blood pressure will be measured before, 6th, and after 12 week of dietary and eccentric exercise intervention.
Time frame: 6th week of intervention
Blood pressure
Morning blood pressure will be measured before, during, and after 12 week of dietary and eccentric exercise intervention.
Time frame: 12th week of intervention
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