Safety and Efficacy of Oshadi D and Oshadi R in Basal Cell Carcinoma Patients Prior to Tumor Excision a Phase 2 Study

Inclusion Criteria: * Age \> 21 years old with tissue confirmed diagnosis of local BCC. * Patient is candidate for surgical excision of the BCC in few months. * BCC lesion ≥10mm in its longest diameter. * Sexually active fertile patients and their partners must agree to use medically accepted methods of contraception during therapy and 3 months after the last dose of the study drugs. * Female patients of childbearing potential must have a negative pregnancy test at screening. * Patient must understand and be willing to give written informed consent prior to any study procedures or evaluations and be willing to adhere to all study schedules and requirements. Exclusion Criteria: * Uncontrolled Intercurrent illness or any history of significant cardiac, renal, neurologic, metabolic, pulmonary, gastrointestinal, hematologic abnormality, chronic hepatic disease or any other disease which in the judgment of the investigator would interfere with the study or confound the results. * Other active cancer disease. * Serum creatinine \> 1.5 mg/dL for males and \>1.4 mg/dL for females. * Female patient who are breastfeeding or have a positive pregnancy test at screening or at any time during the study. * Any acute cardiovascular event during the last 6 months prior to inclusion. * Symptomatic congestive heart failure with ejection fraction \< 30%. * Patient has prothrombin time/International Normalization Ration (PT/INR) or partial thromboplastin time (PTT) test results \> 1.3 UNL. * Hemoglobin ≤ 11 g/dL * Platelets \< 150,000 per microliter * White blood cell count\<3,000 x109/L and/or absolute neutrophils count \<1.5 x 109/L * Significant swallowing disorders. * History of small bowel surgery. * Any history of pelvic or abdominal radiation. * Pre-existing mal-absorption syndrome, irritable bowel syndrome or other clinical situation which could affect oral absorption. * Mental disorders. * Inability to give written informed consent.