The purpose of this study is to compare the effect of TEAS pretreatment and treatment on hepatic and renal dysfunction induced by pneumoperitoneum in patients undergoing laparoscopic surgeries.
Patients were randomly assigned to three groups, control group and two intervention groups, receiving TEAS before and after general anesthesia induction respectively. TEAS was given through electrodes attached to acupoints. The time for TEAS was 30min. Venous blood samples were collected before and 20min after pneumoperitoneum. Hepatic and renal function index including AST, ALT, ALP, BUN, Cr were measured.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
SINGLE
Enrollment
168
Electric stimulation was given through electrode attached to specific acupoints for 30mins before anesthesia induction
Transcutaneous Electrical Acupoint Stimulation was given to the patient at the same time of the start of anesthesia induction for 30mins
Xijing Hospital, Fourth Military Medical University
Xi'an, Shaanxi, China
Incidence of renal or hepatic dysfunction
percentage of patients with renal or hepatic dysfunction
Time frame: 20min after pneumoperitoneum
Change of hepatic function
the increase of hepatic ALT and AST after pneumoperitoneum
Time frame: 20min after pneumoperitoneum
Change of renal function
Change of BUN and Cr after pneumoperitoneum
Time frame: 20min after pneumoperitoneum
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