Description of Insulin Resistance in Patients With Chronic Heart Failure

N/ACompletedNCT02013739

Hasselt University80 enrolled

Overview

The purpose of this study is to describe insulin resistance in a general chronic heart failure population, in combination with muscle strength, body composition and cardiac function. It is assumed that insulin resistance is increased in CHF patient, and that this is related to decreased muscle strength and decreased lean tissue mass.

Study Type

OBSERVATIONAL

Enrollment

Conditions

Chronic Heart Failure

Eligibility

Sex: ALL

Medical Language ↔ Plain English

Inclusion Criteria: * diagnosis of chronic heart failure for at least 6 months, * clinically stable (not hospitalized) for more than 3 months prior to the onset of the study, Exclusion Criteria: * glucose lowering medical therapy

Locations (1)

Hasselt University

Hasselt, Limburg, Belgium

Outcomes

Primary Outcomes

Glucose tolerance

glucose and insulin concentration measurements in blood during oral glucose tolerance test

Time frame: day1

Secondary Outcomes

HbA1c, blood lipids, BNP

Time frame: day 1

Muscle strength: maximal strength tested on a isokinetic dynamometer

Time frame: Day 1

Body composition: dual energy x-ray absorptiometry

Time frame: Day 1

cardiac function: echocardiography, retrospective from hospital files

Time frame: retrospective

Health-related quality of life: MLHFQ and Eq5d

Time frame: Day 1

Data from ClinicalTrials.gov

This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.