Low Flow Anaesthesia, is There a Difference Between 2 Modern Anaesthetic Machines Using Different Gas Reservoir

N/ATerminatedNCT02013869

Jan Jakobsson40 enrolled

Overview

To study the Flow-I breathing circle during low flow general anaesthesia, whether this non-below system has advantages reduced time to reach Et 1MAC (minimal alveolar concentration) and lower consumption of inhaled agent

Assessing whether there are clinical differences in anaesthetic performance between standard anaesthesia workstation including a below and the new Flow-I device without a below

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

BASIC_SCIENCE

Masking

SINGLE

Enrollment

Conditions

General Anaesthesia

Interventions

Flow-I, a modern anaesthetic machine without a bag/below/gas reservoir for compression of insufflation gasDEVICE

Desflurane Dialed setting 18 % on the machine gas vaporized

Asys, a anaesthetic machine with a bag/bellow for compression of gas to be insufflatedDEVICE

Desflurane dialed 18% on the machine gas vaporized

Eligibility

Sex: ALLMin age: 18 YearsMax age: 65 Years

Medical Language ↔ Plain English

Inclusion Criteria: ASA 1-2 patient 18 - 65 years scheduled for elective surgery Exclusion Criteria: ASA \> 2 heart failure COPD

Locations (1)

Danderyds Hospital

Stockholm, Sweden

Outcomes

Primary Outcomes

Time to reach 1.5 MAC (minimal alveolar concentration) Et

The time needed, seconds, to increase the end tidal desflurane concentration during wash-in from a 1 MAC to a 1.5 MAC with a constant fresh gas flow of 1 L/min and the vaporiser set a 3 MAC ( minimal alveolar concentration) (18%) will be compared between the two study groups

Time frame: 1 hour

Secondary Outcomes

amount of inhaled agent consumed ml/min

The vaporiser will be weighed before and after each case and the amount of vapor, desflurane, consumed during the anaesthesia will be calculated Gr/min.

Time frame: 5 hours

Postoperative Quality of Recovery

Quality of recovery will be followed during the first 72 hours after anaesthesia

Time frame: 72 hours

Data from ClinicalTrials.gov

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