We propose a new wash-in technique for desflurane low flow anesthesia with fresh gas flow of O2:N2O 1:1 L/min with desfluraene 12%. The objective of this study is to identify time to achieve alveolar concentration of desflurane at1, 2, 3, 4, 5 and 6%.
The benefits of low flow anesthesia are economic, less pollution, more heat and humidity preservation but it requires appropriate wash-in phase. The current wash-in protocols are complicated and time consuming. We propose a new 1-1-12 desflurane wash-in protocol which is more simple and predictable. The objective of this study is to identify time to achieve alveolar concentration of desflurane at 1, 2, 3, 4, 5 and 6% with 1-1-12 wash-in protocol. All patients will receive iv propofol 2 mg/kg as induction agent and succinyl choline 1.5 mg/kg for intubation. Then the ventilation will be controlled to achieve end-tidal CO2 30-35 mmHg with O2:N2O 1:1 L/min with desflurane 12%. Time to achieve alveolar concentration of desflurane at 1, 2, 3, 4, 5 and 6% will be recorded and analyzed. After that, the concentration of desflurane and anesthetic technique will be adjusted to requirement of anesthesiologist.
Study Type
OBSERVATIONAL
Enrollment
106
wash-in phase during start of low flow anesthesia
Srinagarind Hospital
Khon Kaen, Thailand
Time (in second) to achieve alveolar concentration of desflurane 1, 2, 3, 4, 5 and 6%
Time frame: participants will be followed until alveolar concentration of desflurane reaches 6%, as expected of 15 minutes
Heart rate
Time frame: participants will be followed until alveolar concentration of desflurane reaches 6%, as expected of 15 minutes
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