Worm Study: Modifier Genes in Sudden Cardiac Death

Inclusion Criteria (mutation carrier group): * Age ≥ 18 years. * Heterozygous or homozygous carriership of SCN5A-delPhe1617. * Confirmed kinship to the founder population by haplotype analysis using predefined microsatellite markers. * Written informed consent. Inclusion Criteria (non-mutation carrier group): * Age ≥ 18 years. * Non SCN5A-delPhe1617 genotype. * Confirmed kinship to the Founder Group by haplotype analysis using predefined microsatellite marker. * Written informed consent. Inclusion criteria Spouse Group * Age ≥ 18 years. * Biological parent of SCN5A-delPhe1617 positive subject participating to the Worm Study, and not belonging to study group 1 or 2. * Written informed consent. Exclusion Criteria: * Age ≥ 18 years. * Biological parent of SCN5A-delPhe1617 positive subject participating to the Worm Study, and not belonging to study group 1 or 2. * Written informed consent.