Thrombectomy Under Reopro Versus Alteplase to Treat Stoke

Inclusion Criteria: * Clinical signs consistent with acute ischemic stroke \< 4.5 hours * Cerebral infarction and middle cerebral artery occlusion, without any hemorrhage documented by MRI or CT * 4 \< National Institute of Health Stroke Score (NIHSS) \< 25 * age \> 18 years * no prestroke functional dependance : modified Rankin score ≤ 2 * subject or subject's legally authorized representative has signed and dated an Informed Consent Form according to french regulations and ethic committee. Exclusion Criteria: * pregnant or lactating female * coma (vigilance NIHSS \> 1) * epilepsy * recent history of stroke * anticoagulant therapy or International Normalized Ratio (INR) \> 1.7 ; heparin therapy within past 24 hours and Temps de Cephaline Activee (TCA) extension * previous subarachnoid hemorrhage or clinical presentation suggesting a subarachnoid hemorrhage, even if initial CT or MRI scan are normal * known hereditary or acquired hemorrhagics diathesis, coagulation factor deficiency * uncontrolled hypertension defined as systolic blood pressure ≥ 185 millimeters of mercury (mmHg) or diastolic blood pressure \> 110 mmHg at time of admission and time of threat * lumbar ar arterial puncture within past 7 days * major surgery within past 2 months * gastrointestinal hemorrhage or urinary hemorrhage * myocardial infarction within past 21 days * pericarditis within past 3 months * suspicion of bacterial endocarditis within past 3 months * previous of aortic dissection * baseline lab values : TCA \> 40, platelets \< 100 000/mm3, glucose \< 3 mmol/l or \> 22 mmol/l * hepatic insufficiency * CT or MRI evidence oh hemorrhage * CT or MRI evidence of mass effect or intra-cranial tumor * CT showing hypodensity or MRI showing hyperdensity involving greater than 1/3 of the middle cerebral artery territory (ASPECT score \< 7)