A Focused Registry on Anterior Cervical Interbody Spacer ACIS

Inclusion Criteria: * Age 21 years or older * Degenerative cervical condition that requires anterior decompression and fusion in a single or multiple levels * Degenerative cervical disc disease C3 through Th1 or * Ruptured and herniated discs C3 through Th1 * Ability to understand the content of the patient information / informed consent form * Willingness and ability to participate in the registry according to the registry plan (RP) * Signed and dated IRB / EC-approved written informed consent Exclusion Criteria: * Spinal tumor * Osteoporosis * Cervical trauma and instability * Any not medically managed severe systemic disease (ie. infection) * Recent history of substance abuse (ie, recreational drugs, alcohol) that would preclude reliable assessment * Pregnancy or women planning to conceive within the registry period * Prisoner * Participation in any other medical device or medicinal product clinical investigation or registry within the previous month that could influence the results of the present registry Intraoperative exclusion criteria: * Intraoperative decision to use implants other than the device under investigation