This is a study comparing the effect of erythromycin or metoclopramide, 2 prokinetic drugs (Drugs which are known to speed up the emptying of the stomach or in other words to move the blood out of the stomach faster) given before endoscopy to patients with upper Gastrointestinal bleeding compared to patients who will not receive either of these medications before their endoscopy.
To compare the efficacy of pre-endoscopic interventions namely erythromycin, metoclopromide vs control in improving the outcomes of endoscopy in ICU patients admitted upper GI bleeding. Specific aims: 1. Wither erythromycin, metoclopromide vs control can enable visualization of the entire gastric mucosa . 2. Wither erythromycin, metoclopromide vs control can improve the quality of stomach and duodenum visualization: using the scoring system by Fossard et al
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
DOUBLE
Enrollment
4
Texas Tech University Health Science Center
El Paso, Texas, United States
Erythromycin, Metoclopromide vs Control Enabling Visualization of the Entire Gastric Mucosa .
Whether erythromycin, metoclopramide versus control can enable visualization of the entire gastric mucosa .
Time frame: 45 minutes
Erythromycin, Metoclopromide vs Control Improving the Quality of Stomach and Duodenum Visualization
Whether erythromycin, metoclopramide vs control can improve the quality of stomach and duodenum visualization: using the scoring system by Fossard et al
Time frame: 45 minutes
Source of Bleeding
Ability to identify the source of bleeding
Time frame: 45 minutes
Second-look Endoscopy
Need for second-look endoscopy
Time frame: 48 hours
Blood Units Transfused
Mean number of blood units transfused
Time frame: 48 hours
Mortality
All cause mortality
Time frame: 30 days
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