The Purpose of A Multicenter, Randomized, Double-blind, Placebo-controlled to Evaluate the Efficacy, Safety and Pharmacokinetics of MG in Patients With alcoholic Fatty Liver Disease and Alcoholic Hepatitis.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
DOUBLE
Enrollment
90
Hanyang university Hospital
Guri-si, Gyeonggi-do, South Korea
Change from Baseline in AST at 14weeks
To evaluate the liver function to assess improvement of the MG on change in AST lab value assessed from baseline to 12 weeks in patients with Alcoholic fatty liver disease
Time frame: 14Weeks
Number of Participants with Adverse Events (Safety)
Adverse Event: Physical examine, Lab test, Vital sign, ECG, symptom, start day and time, end day and time, severity, progress, outcome, relation with investigational product.
Time frame: 14weeks
To evaluate ALT normalization
To evaluate ALT normalization assessed by comparing the percentage.
Time frame: 14weeks
To evaluate AST normalization
To evaluate AST normalization assessed by comparing the percentage.
Time frame: 14weeks
change in AST, ALT, total lab billirubin lab value
To evaluate the efficacy of the MG on change in AST, ALT, total lab billirubin lab value assessed from baseline to 4, 8, 12 weeks in patients with Alcoholic fatty liver disease
Time frame: 14weeks
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