Efficacy and Safety of Rebel Reliever Brace in Patients With Symptomatic Medial Knee Osteoarthritis

Main Inclusion Criteria: * Male or female over 18 years * BMI \< or egal to 35kg/m2 * symptomatic gonarthrose defined by a recurrent pain to the walk on 30 days during the last 2 months before the inclusion with radiological findings (grade II to IV on Kellgren-Lawrence) * diagnosis of medial femoro-tibial knee osteoarthrosis * patient with global pain intensity during the last 24hours \> or egal 40 mm (EVA) at the day of selection Main Exclusion Criteria: * femoro-patellar predominant arthrosis * septic arthritis * metabolic arthropathies * chronical rheumatismal diseases * other knee diseases * symptomatic coxarthrosis * controlateral gonathrosis with corticoids injections * any other serious disease which may interfere with the results * psychiatrics disorders * skin lesions or dermal pathologies * venous or arterial disorders * sensitivity disorders in the lower limbs (diabetes mellitus..) * paracetamol intolerance * hyaluronic acid or corticosteroid intra-articular injection in the last month prior to inclusion * on going knee viscosupplementation at inclusion * slow acting OA drugs (if started in the last 2 months prior to inclusion) * opioids, corticosteroids, or NSAIDs intake in the last 48 hours prior to inclusion * pregnant women of with no contraception * hepatic or renal insufficiency