Investigators evaluated the effect of intranasal ketamine or alfentanil addition to oral midazolam for prevention of emergence agitation.Seventy-eight, 1-8 year-old children, undergoing urological surgery with sevoflurane anesthesia was included in the study. All the children received oral midazolam 0.5 mg/kg 40 minutes before anesthesia induction then enrolled to one of the study groups, randomly. Ketamine group (Group MK; n=26) patients were given 2mg/kg intranasal ketamine whereas, alfentanil group (Group MA; n=25) were given 10microgram/kg intranasal alfentanil 8-10 min before the induction of anesthesia. Saline group (Group MS; n=27) received intranasal isotonic saline.Parental separation, mask acceptance were evaluated with a 4- point scale. Emergence agitation was evaluated with Pediatric Anesthesia Emergence Delirium score.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
PREVENTION
Masking
TRIPLE
Enrollment
78
Group M
Group MA
Group MK
Yeditepe University Hospital
Istanbul, Turkey (Türkiye)
Pediatric Anesthesia Emergence Delirium (PAED) score
Emergence agitation was evaluated using the Pediatric Anesthesia Emergence Delirium (PAED) score
Time frame: 7 months
Parental separation score
Parental separation were evaluated with a 4- point scale in the preoperative period
Time frame: 7 months
Mask acceptance
The ease of mask acceptance were evaluated with a 4- point scale in the preoperative period
Time frame: 7 months
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