Phase 1 Study of Topical Ocular PAN-90806 for Neovascular AMD

Inclusion Criteria: * Diagnosis in the study eye of active, pathologic, newly diagnosed and previously untreated, subfoveal choroidal neovascular (CNV) lesions secondary to neovascular AMD * Aged 50 years or older * Demonstrate the ability, or have a family member who is willing and able, to instill topical ocular drops in the study eye Exclusion Criteria: * No prior ocular or systemic treatment or surgery for neovascular AMD in the study eye * History of or current clinical evidence in the study eye of: * aphakia * diabetic macular edema * any ocular inflammation or infections * pathological myopia * retinal detachment * advanced glaucoma * significant media opacity, including cataract * History or evidence of the following surgeries in the study eye: * penetrating keratoplasty or vitrectomy; * corneal transplant; * corneal or intraocular surgery within 3 months of Screening * Uncontrolled hypertension despite use of antihypertensive medications * Participation in any investigational drug or device study, systemic or ocular, within past 3 months * Women who are pregnant or nursing * Known serious allergies or hypersensitivity to the fluorescein dye used in angiography or to the components of the PAN-90806 formulation