Hydros and Hydros-TA Joint Therapy for Pain Associated With Knee Osteoarthritis

Inclusion Criteria: * Have radiographic evidence within the prior 6 months, as shown in the radiology reports, of OA grade 2 or 3 using Kellgren-Lawrence Grading for OA. * Symptoms in the index knee for at least 12 months. * Fully ambulatory Subject (ability to perform a 15 meters walk test). * Male and female Subjects 40 through 85 years of age. Exclusion Criteria: * BMI \>40 kg * Secondary OA (acute knee injury, rheumatoid arthritis, gout, history of joint infection, osteonecrosis, chronic fibromyalgia) or other chronic autoimmune disease. * Intra articular steroid therapy in last 3 months * Intra articular viscosupplementation in last 6 months