The purpose of this study is to help the researchers understand if using a soy supplement impacts cardiovascular disease risk factors in patients with subclinical hypothyroidism.
This pilot trial is a double blind, randomized, parallel arm trial. Eighty participants with subclinical hypothyroidism will be randomized to consume either soy protein isolate or milk protein isolate for 8 weeks.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
NONE
University of Kansas Medical Center
Kansas City, Kansas, United States
Changes in the cardiometabolic profile
Evaluate the role of isoflavone intake on cardiovascular disease.
Time frame: Change from Baseline to Week 8
Change in thyroid function
Safety will be monitored through measuring thyroid stimulating hormone (TSH) and free thyroxine (T4) in participants while on the study.
Time frame: Change from Basesline to 8 Weeks
Change in thyroid function
Safety will be monitored through measuring thyroid stimulating hormone (TSH) and free thyroxine (T4) in participants while on the study.
Time frame: Change from Basesline to 4 Weeks
Changes in the cardiometabolic profile
Evaluate the role of isoflavone intake on cardiovascular disease.
Time frame: Change from Basesline to 4 Weeks
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