Local injection of 5-fluorouracil into a chalazion (stye) is as effective as local injection of triamcinolone (steroid) and incision and curettage for treatment of chalazia.
This is a prospective randomized interventional study comparing four current standard-of-care treatments for chalazia: incision and curettage, local injection of triamcinolone, local injection of 5-FU, and local injection of combination triamcinolone/5-FU.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Enrollment
120
If the chalazion is present at follow-up visit, another injection of 5-FU will be given.
If chalazion present at follow-up, another Triamcinolone injection will be done.
If chalazion present at follow-up visit, patient will be randomized to receive local injection of either triamcinolone, 5-FU, or triamcinolone/5-FU mixture.
University of Washington Eye Institute at Harborview
Seattle, Washington, United States
RECRUITINGSize of chalazion
Time frame: 4 weeks
This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.
If chalazion persists at follow-up visit, another injection of triamcinolone/5-FU mixture will be done.